Vinnie Tortorich

Fitness Confidential Podcast


Caveat mTOR with Dr. Anthony Chaffee – Episode 2444

by Vinnie Tortorich

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Feb022024
EPISODE-2444-CAVEAT-mTor

Episode 2444 – On this Friday’s show Vinnie Tortorich welcomes Dr. Anthony Chaffee and they discuss cholesterol, ketones, claims of caveat mTOR, and more.

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Ketones as Fuel

NOTE: This episode is a load of information—grab a pen and paper, you may want to take notes!

  • They open up chatting about the fitness of prominent low-carb doctors vs. vegan doctors. (2:00)
  • Being lean and fit by eating right and staying active while growing older is important. (7:00)
  • Your body only takes 4 grams of sugar at any one time; anything above that your body will treat as a toxin. (10:30) 
    • You need to eat the right things or your body will deteriorate.
    • Every facet of your life will be improved by living healthfully. (13:00)
  • Vinnie shares a recent X exchange about bananas. (15:00)
    • The idea of “healthy carbs” is misguided.
  • Anthony explains the biological functions happening with types of cholesterol.
    • He shares an experiment with Oreos by Nick Norwitz.
    • The misinformation is that your brain and body “prefer” sugars because they burn them first.
    • Just because carbs get burned first does not mean they are the better fuel.
      • Ketones are the optimal fuel for your body and brain.
  • A frequent question Vinnie gets in his consultations is about statins. (23:30)
    • Statins haven’t even been proven to reduce the chance of heart disease or stroke.
    • Anthony explains the history and rate of increase of heart disease; for example, the Inuit people. (34:00)
  • Four grams of sugar in the blood looks like a level teaspoon. (43:30) 
    • The ketogenic diet and being fueled by ketones can reverse disease; his example is Pompe disease.
  • They discuss how the body can produce its own sugar if necessary; however, ketones are a more efficient source. (48:30)
    • Athletes on a ketogenic diet can fuel their bodies faster than athletes who depend on sugar and carbs.
    • They chat about carb-loading and how it burdens your body.
  • Vinnie challenges the idea of having to have a fuel belt doing marathons or loading kids up with muffins during soccer games. (1:02:00)

Caveat mTOR

  • They discuss mTOR (mammalian target of rapamycin). (1:05:00)
    • There is still a lot to be learned about mTOR.
  • If you are eating something you are supposed to eat, then your biochemistry should work properly.
  • So, The idea that we are getting damaged by eating food that humans have been eating for millennia (meat) is ridiculous.
    • mTOR is a natural protein kinase that fluctuates in the body.
    • You will never micromanage your biochemistry better than your biochemistry can.
  • Finally, Anthony reads an amazing excerpt about how the introduction of agriculture has affected human health. (1:10:00)
  • Alzheimer’s dementia was observed in the early 1900s; however, no earlier medical literature has described that pathology. (1:12:00)
  • Find him on the “Plant Free MD” podcast and @AnthonyChaffeeMD on social media platforms.
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